My Study Stuff

29/02/2012

Raynaud’s phenomenon

Filed under: Health — anlactunay @ 7:33 AM

• Raynaud’s phenomenon is vasospasm and ischaemia of the fingers and toes in response to cold or emotional stress.
• The digits turn white (ischaemia), then blue (deoxygenation), and finally red (reperfusion)

• Most cases are primary Raynaud’s phenomenon—an exaggerated response to stimuli, with no known underlying cause
• Secondary Raynaud’s phenomenon is usually caused by connective tissue disease such as lupus, and tissue damage is more likely.
• Nifedipine is currently the only drug licensed for use
• Topical nitroglycerin is being assessed in ongoing trials.

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